中国医药指南

目的 分析消栓通脉方穴位贴敷治疗气虚湿阻型下肢深静脉血栓形成患者的疗效。方法 选取2023年8月至2024年8月本院就诊的气虚湿阻证下肢深静脉血栓形成患者80例作为研究对象，用随机数字表法分为观察组、对照组，每组40例，分别采用常规西药及介入治疗和消栓通脉方穴位贴敷治疗。比较两组中医证候积分、患肢围度、D-二聚体和纤维蛋白原（FIB）含量、静脉再通率及血栓弹力图指标。结果 观察组中医证候积分较对照组低（P<0.05）；观察组出院时和出院3个月后，患肢围度改善情况较对照组更优（P<0.05）；与对照组相比，观察组出院时及出院3月后FIB、D-二聚体水平较低（P<0.05）；观察组出院3个月后静脉再通率高于对照组（P<0.05）；与对照组相比，观察组出院时凝血反应时间（RT）较长，血栓最大强度（MA）较低（P<0.05）。结论 消栓通脉方穴位贴敷可有效缓解气虚湿阻型下肢深静脉血栓患者临床症状，改善患肢围度，恢复静脉通畅。

Objective To analyze the effect of acupuncture point patch of eliminating thrombus and vein formula in treating patients with deep vein thrombosis of lower limb with qi deficiency and damp obstruction. Methods Eighty patients with lower extremity deep vein thrombosis due to qi deficiency and dampness obstruction who visited our hospital from August 2023 to August 2024 were selected as the research subjects. They were divided into the observation group and the control group by the random number table method, with 40 cases in each group. They were treated with conventional Western medicine and interventional therapy and acupoint application of Xiaoshuan Tongmai Formula respectively. The TCM syndrome scores, the circumference of the affected limb, the contents of D-dimer and fibrinogen(FIB), venous recanalization rates and thromboelastography indicators of the two groups were compared. Results The TCM syndrome score of the observation group was lower than that of the control group(P<0.05). At discharge and 3 months after discharge, the improvement of the limb circumference in the observation group was better than that in the control group(P<0.05). Compared with the control group, the levels of FIB and D-dimer in the observation group were lower at discharge and 3 months after discharge(P<0.05). The venous recanalization rate of the observation group three months after discharge was higher than that of the control group(P<0.05). Compared with the control group, the coagulation response time(RT) at discharge in the observation group was higher, and the maximum strength of thrombus(MA) was lower(P<0.05). Conclusions The acupoint application of eliminating embolism and clearing the veins can effectively alleviate the clinical symptoms of patients with qi deficiency and damp obstruction type of lower limb deep vein thrombosis,improve the circumference of the affected limbs,and restore the smoothness of the veins.